Antifungal prophylaxis in haematology patients
نویسندگان
چکیده
منابع مشابه
Antifungal Prophylaxis in Immunocompromised Patients
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal prophylaxis in hematological patients is currently regarded as the gold standard in situations w...
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These recommendations have been developed by an expert panel following an evidencebased search of the literature assessing the role of primary antifungal prophylaxis in patients with acute leukaemia or stem cell transplantation. We present results from a questionnaire on the current practice among experts in Europe, show results of the literature search and provide the panel’s recommendations. ...
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van Till and colleagues assessed yeast colonisation, lumping together ‘positive yeast cultures obtained from sputum, stool, urine and/or wound’ [1]. The majority of SDD trials reported positive yeast cultures obtained from surveillance cultures of throat and rectal swabs, whilst the SAP studies mainly assessed positive yeast cultures obtained from diagnostic samples including lower airway secre...
متن کاملCaspofungin as secondary antifungal prophylaxis and subsequent maintenance antifungal prophylaxis therapy in hematological malignancy patients.
AIM This study aimed to investigate the efficacy and safety of caspofungin as secondary antifungal prophylaxis (SAP) and subsequent maintenance therapy for SAP in hematological malignancy patients. METHODS Forty four patients receiving caspofungin for SAP and 43 patients not receiving any SAP agents during their subsequent chemotherapy or HSCT were reviewed retrospectively. The clinical chara...
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F UNGAL INFECTIONS are an important cause of morbidity and mortality in patients with hematologic malignancies. Prolonged neutropenia, impaired cell-mediated immunity, and fungal colonization after the administration of broad-spectrum antibiotics are known predisposing fact o r ~ . “ ~ The risk of invasive fungal infection is particularly high in the setting of allogeneic bone marrow transplant...
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ژورنال
عنوان ژورنال: Clinical Microbiology and Infection
سال: 2006
ISSN: 1198-743X
DOI: 10.1111/j.1469-0691.2006.01607.x